I also lost all of my crypto but only in one of 4 wallets... My supposedly unhackable Ledger Nano S hardware wallet just got cleaned out during the latest firmware update from Ledger, it is version 1.4.2

Here is the reference: https://ledgerwallet.us2.list-manage.com/track/click?u=bcc2126fb4bf3e02256d6c188&id=e11326e3e7&e=090fa3251a

O.K. Ledger recommended that the firmware upgrade be done to add new features so I went ahead and followed the instructions. All went well until I had to re-enter my password (passwords can be any combination of 4-8 digits... mine was 6 digits long) When you enter the password a string of 8 blank entry positions appears on the screen of the Nano. It used to be that you just entered your PW and any remaining blank entries would be checked and you were good to go. This changed during the upgrade so that you now have to manually check the first blank space after you enter your password, before you confirm the entry. Clear as mud... right?

Well, not knowing this I messed up the entry 3 times and the device reset itself. All was not lost because I had the 24 word "key" with which to recover my device... At least in theory according to Ledger.

I entered the key and restored the device only to discover that my various crypto wallets now had a zero balance! Whoa! what happened? Further checks revealed that the receiving addresses of the wallets on the restored Nano were different than before the update/reset/restore events. Hence no crypto or records of any transactions. The wallets had been wiped clean... and now had new addresses. I know what the addresses of the old wallets were because I have records of sending crytpo to them but researching these transactions on the blockchain has proved to be difficult using the search tools that I can find. If anyone out there has expertise on the blockchain and how to research transactions, please let me know by email: willie@startmail.com user Kenji.

People tell me that it is impossible for this to have happened but it did... confirming that old saying, "nothing is impossible". I sympathize with your loss as mine was not that great... I was just experimenting with the NanoS and learning use it so I had not transferred a great amount of crypto to it. As I have said: Crickets from Ledger so far but I will keep you all updated when I hear something.

My final advice is that crypto, at its current stage of evolution, is like the wild west in the USA used to be... a dangerous place for the unwary! So be careful. K